SERUM 25 OH VITAMIN D IN CHILDREN WITH BACTERIAL PNEUMONIA

Abstract

Background: Bacterial pneumonia of is common cause of pediatric mortality and hospital admission.
Different risk factors for pneumonia are there. One possible risk factor is vitamin D deficiency .Objective:
We determined 25 OH-vitamin D in bacterial pneumonia.to evaluate whether its level has relation to
pathogenesis and management of the disease Design: case-control study Methods: 25 OH-vitamin D was
determined by competitive enzyme immunoassay (EIA) commercially available kit in 36 cases with
pneumonia CRP was determined by ELIZA "high sensitive CRP" .ESR done by Wintrobe method The
results were analyzed and compared with 16 controls using SPSS 20 Results: Vitamin D level in pneumonia
cases was significantly lower in patients compared to controls a n d s h o w e d n e g a t i v e c o r r e l a t i o n
w i t h C -r e a c t i v e p r o t e i n and weak negative correlation ESR. Vitamin D did not show any relation to
age, sex, weight or other clinical symptoms as dyspnea and fever Also did not show any relation to RBCs,
Hb, or WBCs .Conclusion: We conclude that level of 25 OH-vitamin D is low in children with bacterial
pneumonia and correlates negatively with CRP with possible relation to disease severity.
Keywords: pneumonia, 25OH vitamin D, bacterial and viral infectio.